Programa
COURSE PROGRAMME
Tuesday, May 24th
13:00-15:30 h REGISTRATION ISPF
16:00-16:30 h OPENING CEREMONY
16:30-17:30 h PLENARY 1. FRANCE. Gain and loss of function in channelopathies: a focus on sodium channels in epilepsy and migraine.
Chair: Florian Lesage
Speaker: Massimo Mantegazza (France)
17:30-18:00 h COFFEE BREAK
18:00-19:30 h PLENARY 2. SPAIN. Conformational plasticity of ion channels: a fluorescence-based approach
Chair: Antonio Ferrer
Speaker: José Antonio Poveda Larrosa y Lourdes Renart
19:30-20:00 h DISCUSSION
20:30-22:00 h DINNER
Wednesday, May 25th
09:30-11:00 h PLENARY 3. ITALY. Investigating the retinal network ex-vivo
Chair: Félix Viana
Speaker: Stefano Di Marco
11:00-11:30 h COFFEE BREAK
11:30-13:00 h PLENARY 4. SPAIN. Modulation of TRPA1 channels by the chaperone Sigma-1Recepetor as a neuroprotective strategy against peripheral neuropathy by chemotherapy
Chair: Ana Gomis
Speakers: Elvira de la Peña and Jorge Fernández Trillo
13:00-13:30 h DISCUSSION AND CLOSING CEREMONY
13:30-16:00 h LUNCH FOR ISPF
CONGRESS PROGRAMME
Wednesday, May 25, 2022
15:00 h REGISTRATION RECI
16:00-16:30 h OPENING CEREMONY
16:30-17:30 h OPENING LECTURE
Chair: Juan A. Rosado
Speaker: Oscar Casis. Universidad del País Vasco
17:30-19:30 h SYMPOSIUM 1. ION CHANNELS IN PHYSIOLOGY AND PATHOLOGICAL CONDITIONS
Chairs: Asia Fernández Carvajal and Antonio Felipe
Presentations (20 +5 min)
• Anticonvulsant and neuroprotective roles of SGK1.1
Teresa Giráldez. U.La Laguna
• Dominant negative effect of an SCN5A variant in native cardiac sodiumchannels
Fabiana S. Scornik. U. Girona
• The Volume-Regulated Anion Channel VRAC: recent physiological andpathological findings
Rosa Planells. Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP)
Short presentations (9+2 min)
• Adenosine modulates Kv1.3 by complementary PKC and PKA pathways indendritic cells
Irene Estadella Perez. U. Barcelona
• Electrophysiological effects of IQM-266 on Itof. Role of cardiac beta subunits
Angela de Benito. Instituto de Investigaciones Biomédicas ‘Alberto Sols’ (CSIC-UAM)
• Revealing the role of the mechanosensitive Piezo1 channel in controllingendosome trafficking for efficient cytokinetic abscission
Julia Carrillo Garcia. U. Pompeu Fabra
• Oxaliplatin time course effect on a pre-clinical in vitro model of male andfemale rat DRG neurons
Eva Mª Villalba Riquelme. IDiBE, U. Miguel Hernández
20:30-22:00 h RECEPTION
Thursday, May 26, 2022
9:00-11:00 h SYMPOSIUM 2. VIRAL PROTEIN CHANNELS
Chair: Vicente Aguilella
Presentations (20 +5 min)
• Viroporins from a historical perspective: still a bone of contention?
José Luis Nieva. UPV-Biofisika, Bilbao
• The envelope protein channel of SARS-CoV-2: structure-function and futureperspectives.
Jaume Torres. Nanyang Tech. U. Singapur
• Electrophysiological characterization of viroporin ion channels regulatedby lipid-protein interactions
Antonio Alcaraz. U. Jaume I, Castellón
Short presentations (9+2 min)
• Controlling the release of apoptogenic factors; the role of viral Bcl2s’transmembrane domains
Luis Martínez Gil. UVA
• Effects of Sars-Cov-2 envelope protein on store-operated channels andcalcium homeostasis in human lung microvascular endothelial cells
Sendoa Tajada. IBMG UVA/CSIC
• The viroporin SARS-CoV-2 envelope protein induces calcium release fromintracellular stores and apoptosis in rat hippocampal neurons
Sara López Vázquez. IBMG UVA/CSIC
11:00-12:00 h COFFEE AT POSTERS
12:00-14:00 h SYMPOSIUM 3. Ca2+ IN HEALTH AND DISEASE
Chair: Juan Antonio Rosado
Presentations (20 +5 min)
• Orai1 facilitates post-ischemic angiogenesis after myocardial infarctionthrough Notch1 signaling pathway
Tarik Smani. IBiS-U. Sevilla
• Store Operated Calcium Entry remodelation in Breast cancer
José Javier López. U. Extremadura
• Calcium Channel remodeling in rat hippocampal neurons aged in vitro
Lucía Nuñez. UVA
Short presentations (9+2 min)
• Polyamine depletion reverses transcriptomic as well as calcium remodelingin colon cancer cells
Enrique Pérez Riesgo. IBGM (CSIC-UVa)
• Orai1α controls TRPC1 channel location and function in HeLa cells.
José Sánchez-Collado. U. Extremadura
• Calmodulin is critical for folding of the Kv7.2 calcium responsive domain asthe nascent peptide exits the ribosome
Arantza Muguruza-Montero. Instituto Biofisika
• The effects of aging on pancreatic β-cell function involve multiple events inthe regulation of insulin secretion
Iván Quesada. IDiBE-UMH
14:00-16:30 h LUNCH AND POSTERS
16:30-18:30 h SYMPOSIUM 4. ION CHANNELS AND PAIN
Chair: Ana Gomis
Presentations (20 +5 min)
•Piezo2 channels: from structure to nociception
Paco Taberner. Inst Neurociencias-UMH/CSIC
• Clues to understanding TRPC5 as a cold-activated channel and its inhibitionby the analgesic duloxetine
Lucie Zimová. FGU-CAS, Praga
•Skin sensory glia as detector cells for pain and touch
Laura Calvo-Enrique. U Salamanca
Short presentations (9+2 min)
• The endocrine disruptor bisphenol A regulates sodium Nav1.7 rampcurrents in mouse dorsal root ganglion neurons and increases nociception
Juan Martínez-Pinna. U. Alicante- IDiBE
• Discovery of new TRPM8 modulators and their therapeutic potential
Alicia Medina. IDiBE-UMH
• Light-gated channel Channelrhodopsin-2 improves neuroregenerativepotential of Neural Precursors Cells after Spinal Cord Injury (SCI)
M.del Mar Sanchez Martín. CIPF-Valencia
• Testosterone-TRPM8 interactions drive pain resilience in a mouse model ofchronic migraine
David Cabañero Ferri. IDiBE-UMH
18:30-19:30 h RECI PLENARY
Chair: Vicente Aguilella
Speaker: Luis Enjuanes. CNB-CSIC, Madrid
20:30-23:00 h CONGRESS DINNER
Friday, May 27, 2022
09:00-11:00 h SYMPOSIUM 5. PHOTOPHARMACOLOGY AND DRUG DISCOVERY
Chairs: Rosario González Muñiz and Francisco Ciruela
Presentations (20 +5 min)
•Enantiopure lactams as NMDA receptor antagonists
María M M Santos. U. Lisboa
• Controlling receptor activity with photoswitchable drugs: basic researchand future therapies
Pau Gorostiza. Inst. for Bioengineering of Catalonia
• Purinergic photopharmacology: towards new therapeutic opportunities
Francisco Ciruela. U. Barcelona
Short presentations (9+2 min)
• Evaluation of the EAR-20 peptide as a positive allosteric modulation ofNMDA receptors
Roberto García. U. Barcelona
• Ion channel based development of biosensors for discovering improvedtreatments for amyotrophic lateral sclerosis
Sara Alicante. Instituto de Biofisika, UPV
• New chiral heterocyclic compounds with potent TRPM8 antagonist activity
Carolina Izquierdo. Instituto de Química Médica, IQM-CSIC
• Structural and functional insights into TRPM8 modulation mediated by theimmunosuppressant macrolide Rapamycin
Khalid Oudaha. Instituto de Neurociencias, UMH-CSIC
11:00-12:00 h COFFEE AT POSTERS
12:00-13:00 h CLOSING PLENARY
Chair: Rosario González Muñiz
Speaker: Robin S. Bon.
• Understanding TRPC1/4/5 channels through chemical/structural biology
13:00-13:30 h CLOSING CEREMONY
13:30-15:30 h LUNCH AND FAREWELL
Ayuda RED2018-102628-T, financiado por: Ministerio de Ciencia, Innovación y Universidades – Agencia Estatal de Investigación